Familial adenomatous polyposis (FAP) is an autosomal dominant condition caused by a mutation in APC tumor suppressor gene (chromosome 5q21). Affected patients have nearly 100 percent progression to colorectal cancer. Solitary congenital hypertrophy of retinal pigment epithelium (CHRPE) and its multi focal variant, congenital grouped pigmentation (bear tracks), are isolated ophthalmic entities and are not associated with FAP and Gardner syndrome. Patients found to have solitary or multifocal CHRPE on ophthalmoscopy can be counselled that they do not have an increased risk of colon cancer compared with that of the general population.
Nene, A. N., Ramteke, P., & Shah, S. (2019). CONGENITAL HYPERTROPHY OF RETINAL PIGMENT EPITHELIUM (CHRPE) WITH TYPICAL ‘BEAR TRACK’ PRESENTATION. Journal of Ophthalmology and Related Sciences, 3(1), 10-11. doi: 10.21608/jors.2019.28322
MLA
Amit ne Nene; Pushpanjali Ramteke; Smitesh Shah. "CONGENITAL HYPERTROPHY OF RETINAL PIGMENT EPITHELIUM (CHRPE) WITH TYPICAL ‘BEAR TRACK’ PRESENTATION", Journal of Ophthalmology and Related Sciences, 3, 1, 2019, 10-11. doi: 10.21608/jors.2019.28322
HARVARD
Nene, A. N., Ramteke, P., Shah, S. (2019). 'CONGENITAL HYPERTROPHY OF RETINAL PIGMENT EPITHELIUM (CHRPE) WITH TYPICAL ‘BEAR TRACK’ PRESENTATION', Journal of Ophthalmology and Related Sciences, 3(1), pp. 10-11. doi: 10.21608/jors.2019.28322
VANCOUVER
Nene, A. N., Ramteke, P., Shah, S. CONGENITAL HYPERTROPHY OF RETINAL PIGMENT EPITHELIUM (CHRPE) WITH TYPICAL ‘BEAR TRACK’ PRESENTATION. Journal of Ophthalmology and Related Sciences, 2019; 3(1): 10-11. doi: 10.21608/jors.2019.28322
)
View on SCiNiTO