RETINAL PIGMENT EPITHELIAL DETACHMENT: THREE CASE REPORTS

Document Type : Review Articles

Authors

1 Ophthalmology Department, Research Institute of Ophthalmology, Giza, Egypt

2 Research Institute of Ophthalmology, Giza, Egypt, E-mail: shoumanaaes@yahoo.co.uk

Abstract

Pigment epithelial detachment (PED) is a common entity in age-related macular degeneration and central serous chorioretinopathy. Nevertheless, it can manifest rarely without an obvious causative factor. The authors report 3 cases of PED that were atypical in terms of pattern and age presentation. The second case is associated with sickle cell disease, which has not been reported in literature as far and that could add to our knowledge of this disease entity. Methods:
The three cases underwent ophthalmological examination, optical coherence tomography, fundus autoflourescence, fundus fluorescein angiography, full-field electroretinogram and visual evoked potential. Full medical evaluation was done. Results: Bilateral ocular fundus examination showed multiple, rounded lesions scattered all over the fundus in three cases and peripheral retinal pigment epithelial pigmentary changes in the periphery in two cases. Medical evaluation showed one case of sickle cell disease. Conclusion: The number of reports on atypical pigment epithelial detachment and their correlation is limited. In addition its occurrence with sickle cell disease in the second case is a novel correlation which has to be reported and followed-up.